SNP in lifespan
Predicting the impact of SNPs on longevity
How can we discriminate the potential impact of missense mutations?
Building upon the tool Global Epistatic Model Predicting Mutational Effect (GEMME) (Laine et al., 2019), PhD candidate Marina Abakarova (cosupervised with Prof. Elodie Laine) built a pipeline for efficiently predicting SNP-associated missense impacts throughout whole proteomes.