Michael Rera

4th floor
25 Rue Hélène Brion
75013, Paris
Trying to understand what ageing is, where it comes from and where it gets us, since 2005. Building the two-phase ageing framework since I first described the Smurf phenotype in Drosophila melanogaster . I started my research group "Understanding The End-of-Life" (UTELife) in 2018.
The core of the research project I am carrying is strongly transdisciplinary, from basic biology, genetics and physiology to bioinformatics and mathematical modeling.
Research team
Savandara Besse, postdoc
Hayet Bouzid, 1st year PhD student co-supervised with Clément Carré (MCF, SU)
Marina Abakarova, 2nd year PhD student co-supervised with Elodie Laine (MCF, SU)
Alumni
Céline Cansell, PhD
Flaminia Zane, PhD (graduated may 2022)
Fanny Bain, Engineer
news
Nov 5, 2023 | New article online at Genome Biology and Evolution, first article from Marina Abakarova’s PhD Alignment-based protein mutational landscape prediction: doing more with less |
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Oct 13, 2023 | New article online @AgingCell Smurfness-based two-phase model of ageing helps deconvolve the ageing transcriptional signature
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Aug 16, 2023 | New preprint on figshare, Two phases model of ageing in mice: towards a better identification of age-related and late-life metabolic decline [Registered Report Stage 1 Protocol] |
Nov 24, 2022 | New preprint on bioRxiv, Smurfness-based two-phase model of ageing helps deconvolve the ageing transcriptional signature |
Sep 22, 2022 | An article about the mission we conducted in Costa Rica Tropen Station in The Conversation. |
selected publications
- Two phases model of ageing in mice: towards a better identification of age-related and late-life metabolic decline [Registered Report Stage 1 Protocol]Aug 2023
- Positive selection of senescence through increased evolvability: ageing is not a by-product of evolution.bioRxiv Aug 2022
- Ethical and social implications of approaching death prediction in humans-when the biology of ageing meets existential issuesBMC Medical Ethics Aug 2020
- Two phases of aging separated by the Smurf transition as a public path to deathScientific reports Aug 2016
- A new, discontinuous 2 phases of aging model: Lessons from Drosophila melanogasterPloS one Aug 2015
- Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in DrosophilaProceedings of the National Academy of Sciences Aug 2012